UK allows to develope mitochondrial DNA switching techniques for avoiding deseases

In a historic decision, the United Kingdom goverment has voted  a gene-therapy technique that could help women to avoid passing genetic defects onto their children.

The vote, decided by 382 members of parliament casting in favour and 128 against, is expected to lead to the United Kingdom becoming the first country in the world to allow the transfer of DNA from diseased human eggs to healthy ones in the clinic.

This technique, known as mitochondrial replacement or three-person in vitro fertilization, aims to prevent women passing on harmful mutations in their mitochondria, the cell’s energy-producing structures. An estimated 1 in 5,000 children are born with diseases caused by such mutations. All mitochondrial DNA is inherited from the mother, and some women carry harmful mitochondrial mutations without experiencing symptoms themselves

DNA2 (1) Here are the two different techniques for mitochondrial DNA switching

The new law would not take effect until October. Moreover, clinics wishing to offer the treatment must apply for approval from United Kingdom’s fertility regulator, the Human Fertilisation and Embryology Authority (HFEA). And before giving a green light, the HFEA will probably want further evidence that the procedure is safe, and it is likely to vet applications on a case-by-case basis.

images This is why mitochondrial DNA deseases are always heritated from the mother

This thechnique will be a great advance for fighting a lot of common deseases that can be produced by mitochondrial DNA, such as diabhetes,parkinson,muscular deseases,variated syndroms…

Many reproductive biologists see this as a step that will affect the field on a global scale. “We’ve been hoping that the UK will take the lead,” says Shoukhrat Mitalipov, a The United Kingdom was one of the few countries that explicitly banned mitochondrial replacement by law.

The UK vote is the culmination of a decade-long effort on the part of researchers, advocates and funders to change the law banning mitochondrial replacement .These procedures were only legal for research purposes; UK law had explicitly prohibited their use in human reproduction.

This new voting will open a path for the approving of the mitochondrial DNA replacement in more countries, like Australia and the USA and it’ll be a really useful treatment that will avoid thousands of heavy deseases

Personal opinion

I think that this kind of advances on health techniques should be more supported by the goverments, because they can avoid a lot of deadly deseases, and they shouldn’t be delayed because of ethical questions, because human life must be above everything

This page explains in a better way the DNA switching technique





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3 Responses to UK allows to develope mitochondrial DNA switching techniques for avoiding deseases

  1. You have chosen a very important piece of news, because biology is progressing faster than ever, revealing new ethical dilemmas; society must discuss it, decide and translate their decisions into laws. BUT, as you write about bioethics and legislation, there is not a direct academic paper, you have not the compulsory “original source”. Both articles you linked come from the “News” section in Nature.

    > However, It’s quite easy to find an academic paper on this type of therapy, simply following the link provided in your references (just one step, using the second paper you’ll go to a 2012 article). Find it, link it as original source, and write a paragraph using data extracted from it.

    > Personal opinion, this paragraph is absolutely essential in this type of issues, and you don’t have written it!

    > There’re two spelling mistakes in your headline, correct them as this is the most conspicuous place in a post!

    > Images.- Captions should include the source of the image, specially coming from an article already linked. Edit the image to type the text in the box reserved for captions to avoid format obstacles. And add some information to explain their contents. Can you link the second image to a site with better resolution?.

  2. juanjo fernandez castro di:

    I found a good article about the techniques and I wrote muy opinión about this topic

  3. > One spelling mistake remaining in the headline
    > You don’t use information from your new article, which is not an academic one; you don’t activate its link.
    > Images and captions?

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